Duodenal Ulcer Bleeding Endoscopic Treatment

Hemorrhage due to Duodenal Ulcer Endoscopic managment Endoscopic Therapy Endoscopic injection sclerosis: effective treatment for bleeding peptic ulcer. Endoscopic injection therapy to prevent rebleeding from peptic ulcers with a protruding vessel Injection Therapy with absolute alcohol we used 1/4 cc injected in each quadrant of the ulcer as seen in the video clip. The injection of sclerosants and adrenaline in a bleeding peptic ulcer is known to arrest bleeding in the majority of patients. However, there are very few studies on this subject. Injection therapy was carried out using absolute alcohol Injection with solutions of diluted epinephrine (1:10,000) is widely used because of its simplicity. All that is required is a sclerotherapy needle, and the technique is simple. The principal mechanism of action by which diluted epinephrine solutions work is a tamponade effect induced by the volume of solution injected. It is, therefore, logical that in a recent study, a large volume (35-45 ml) epinephrine injection appeared to be more effective than a standard volume (15-25 ml) injection. Solutions of agents other than epinephrine, such as polidocanol, saline and even dextrose, can produce the same effect. In spite of the large body of published literature, no single solution for endoscopic injection has been shown to be superior to another in achieving hemostasis. The use of sclerosants (including absolute alcohol) in injection therapy for bleeding ulcers should, however, be discouraged: extensive and uncontrolled tissue necrosis caused by sclerosants injected to the ulcer base can result in ulcer perforation and complications relating to adjacent tissues.