Epilepsy, Animation.

18.10.2016
Types of seizures, symptoms, pathology (mechanism) of epilepsy, causes and treatments. This video and other related images/videos (in HD) are available for instant download licensing here : https://www.alilamedicalmedia.com/-/galleries/images-videos-by-medical-specialties/neurology ©Alila Medical Media. All rights reserved. All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition. Epilepsy is a group of neurological diseases characterized by recurrent seizures. Seizures happen as a result of a sudden surge in the brain’s electrical activities. Depending on which part of the brain is affected, a seizure may manifest as loss of awareness, unusual behaviors or sensations, uncontrollable movements or loss of consciousness. The brain is a complex network of billions of neurons. Neurons can be excitatory or inhibitory. Excitatory neurons stimulate others to fire action potentials and transmit electrical messages, while inhibitory neurons SUPPRESS this process, preventing EXCESSIVE firing. A balance between excitation and inhibition is essential for normal brain functions. In epilepsy, there is an UP-regulation of excitation and/or DOWN-regulation of inhibition, causing lots of neurons to fire SYNCHRONOUSLY at the same time. If this abnormal electrical surge happens within a limited area of the brain, it causes PARTIAL or FOCAL seizures. If the entire brain is involved, GENERALIZED seizures will result. Partial seizures subdivide further to: - Simple partial: - Complex partial Generalized seizures subdivide further to: - Absence seizures: - Tonic seizures - Atonic seizures, drop attacks - Clonic seizures - Myoclonic seizures - The most common and also most dramatic are tonic-clonic seizures, also known as convulsive seizures, which are combinations of muscle stiffening and jerking. This type is what most people relate to when they think of a seizure. It also involves sudden loss of consciousness and sometimes loss of bladder control. A tonic-clonic seizure that lasts longer than 5min requires immediate medical treatment. Epilepsy may develop as a result of a brain injury, tumor, stroke, previous infection or a birth defect. Generalized seizures that start in childhood are likely to involve genetic factors. Epilepsy due to a single gene mutation is rare. More often, an interaction of multiple genes and environmental factors is responsible. Hundreds genes have been implicated. Examples include genes encoding for GABA receptors – major components of the inhibitory circuit, and ion channels. Many genetic disorders that cause brain abnormalities or metabolic conditions have epilepsy as a primary symptom. The cause of epilepsy is unknown in about half of cases. Diagnosis is based on observation of symptoms, medical history, a

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